🧠 Anxiety & Mood Disorders Medications (불안·우울·양극성 약물 총정리)
안녕하세요! 오늘의 간호사 Haley 입니다 😊
오늘은 불안(Anxiety), 우울(Depression), 양극성장애(Bipolar Disorder)에 사용되는 대표 약물들을
간호 포인트 중심으로 정리했습니다.
Each medication includes Korean and English descriptions for nurses and students.
💊 Anxiety Medications (항불안제)
| Class (분류) |
Examples (대표 약물) |
Key Points (핵심 포인트) |
Cautions (주의사항) |
Benzodiazepines (-lam, -pam) |
Diazepam, Lorazepam, Alprazolam |
• Fast onset (효과 빠름)
• Used for anxiety, seizure, alcohol withdrawal
• Causes sedation/drowsiness (진정, 졸림)
|
🚫 Avoid driving or machinery (운전/기계 금지)
🌙 Take before sleep (취침 전 복용)
🧯 Antidote: Flumazenil
|
| Barbiturates |
Phenobarbital |
• Long duration (효과 오래감, 5일 정도 지속)
• Slow excretion from the body
|
⚠️ Causes hypotension ↓, RR ↓ (혈압·호흡 저하)
🛑 Risk of death if over-sedated → Notify immediately
|
| Buspirone |
Buspirone |
• Non-sedative, non-addictive (비진정성, 의존성 없음)
• Takes 2–4 weeks for full effect (효과 느림)
|
✅ Can drive safely (운전 가능)
❌ Not for acute anxiety (급성 불안엔 부적절)
🚫 No alcohol (알코올 금지)
|
Common Rule: Avoid alcohol with all anti-anxiety drugs.
모든 항불안제는 알코올 병용 시 진정·호흡억제 위험이 증가합니다.
💊 Antidepressants (항우울제)
⚠️ Initial Risk: Suicidal thoughts may increase during first few weeks.
약 시작 초기 몇 주간 자살사고 증가 가능 → 즉시 보고.
Do not stop abruptly — taper gradually (급중단 금지, 서서히 감량).
- 🚫 SSRI + St. John’s Wort → Serotonin Syndrome
- 🚫 MAOI + Other antidepressants → 2-week washout needed
- 📉 BP drop, ⚖️ weight gain common
1️⃣ SSRI (Selective Serotonin Reuptake Inhibitors)
Fluoxetine, Sertraline, Paroxetine, Citalopram, Escitalopram (-ine, -pram)
- Slow onset (2–4 weeks), taper gradually
- Side effects: sexual dysfunction, ↑ suicide risk
- Serotonin Syndrome: sweating, fever, tremor, hyperreflexia, mydriasis, agitation, tachycardia, HTN
- ⚠️ Energy ↑ but still depressed → Notify immediately
2️⃣ SNRI (Serotonin–Norepinephrine Reuptake Inhibitors)
Duloxetine, Venlafaxine
- Improves pain & sleep (통증·수면 개선)
- Used for fibromyalgia, neuropathic pain
3️⃣ TCA (Tricyclic Antidepressants)
Amitriptyline, Imipramine
- For depression, anxiety, neuropathy
- Anticholinergic effects: photophobia, urinary retention, dry mouth, constipation
🕶️ Sunglasses & artificial tears
🍬 Chewing gum for dry mouth
🥗 High-fiber diet for constipation
🚶♀️ Change position slowly (기립성 저혈압 주의)
4️⃣ MAOI (Monoamine Oxidase Inhibitors)
Phenelzine, Selegiline, Isocarboxazid
- 💣 Risk of hypertensive crisis: headache, agitation
- 🚫 Avoid tyramine foods: wine, cheese, beer, sausage, chocolate (2w before & after)
- 🚫 Avoid OTC meds (NSAIDs, antacids, etc.)
- 🧠 2-week washout before switching antidepressants
🌙 Atypical Antidepressants (비전형 항우울제)
| Drug (약물) |
Key Points (특징 / 간호 포인트) |
| Trazodone |
• Sleepy (졸림 많음) → useful for insomnia
• Avoid alcohol / other sedatives
• Risk of hypotension
⚠️ Priapism ≥4hrs → Notify immediately
|
| Bupropion (XL/SR) |
• Side effects: headache, insomnia
• Don’t double up if missed dose
• ❌ Don’t crush, chew, or cut XR/SR tablets
|
💫 Bipolar Disorder (양극성 장애)
1️⃣ Carbamazepine
- Used for bipolar & trigeminal neuralgia
- Fever/sore throat → agranulocytosis → Notify
- Decreases oral contraceptive effectiveness → use alternative
2️⃣ Valproic Acid
- Liver toxicity: jaundice, ↑AST/ALT
- Thrombocytopenia (low PLT)
- ❌ Contraindicated in pregnancy
- ❌ Do not stop abruptly
3️⃣ Lithium ★★★★★
- Therapeutic: 0.6–1.2 mEq/L (≥1.5 → Toxic)
- Monitor Cr >1.3, urine output <30ml hr="" li="" toxic="">
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- 🚫 Avoid in dehydration, hyponatremia, diarrhea/vomiting
- 🚫 Avoid diuretics, anticholinergics, NSAIDs
- 💧 Maintain hydration & sodium intake
- For dry mouth → ice chips, gum, water, oral care
- ⚠️ Extreme urination/thirst → Notify immediately
📋 Summary Table (요약)
| Category |
Key Nursing Point |
Must Remember |
| Benzodiazepine |
Fast effect, sedation |
🚫 Driving / Flumazenil antidote |
| Barbiturate |
Long duration, risk of over-sedation |
Monitor BP↓, RR↓ → Notify |
| Buspirone |
Non-sedative, low dependence |
Onset 2–4 weeks |
| SSRI |
Slow onset, ↑ suicide risk |
❌ St. John’s Wort |
| SNRI |
Pain & sleep improvement |
Fibromyalgia use |
| TCA |
Anticholinergic s/e |
Dry mouth, constipation care |
| MAOI |
Avoid tyramine foods |
Hypertensive crisis risk |
| Lithium |
Hydration & Na balance crucial |
❌ Diuretics, NSAIDs |
💡 Nursing Tips:
Monitor for suicidal thoughts early weeks.
Do not stop suddenly — taper gradually.
Avoid alcohol and report abnormal symptoms immediately.
정리: 오늘의 간호사 Haley ·
📌 본문 내용은 오늘의 간호사 Haley의 저작물로 무단 복제·배포를 금합니다.
#MentalHealth #NursingPharmacology #AnxietyMeds #Antidepressants #Lithium #간호약물정리 #정신과간호